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Electrospun Nanocomposite from Poly(lactic acid) and Cellulose Nanocrystals  
Electrospun Nanocomposite from Poly(lactic acid) and Cellulose Nanocrystals
資料類型: PDF文件
關(guān)鍵詞: electrospinning  cellulose  nanocrystals  nanocomposites  poly  (lactic  acid)  
(pla)  
資料大小: 106K
所屬學(xué)科: 分子表征
來源: 第六屆亞歐研討會上處理和性能增強聚合物會議文集(2013.6.2-6 武漢)
簡介:
Poly(lacticacid)(PLA),abiodegradablepolymerproducedfromrenewablebiomassresources9hasbeensuccessfullyelectrospuntoformmicrofibersornanofibersforbiomedical(e.g.,tissueengineering)andotherrelatedapplicationscl‘2].ThescaffoldsconsistingofelectrospunPLAfiberspossesseddesiredporousstructureandgoodbiocompatibilityc3].However,pureelectrospunPLAfibersnormallyhavepoormechanicalpropertiesandlowthermalandchemicalstability,whichlimittheirapplicationinmanyfields.Hence,enhancingthemechanicalandchemicalpropertiesofPLAfiberswithnano-materialsisdesirableformanyengineeringapplications.Inthiswork,fibrousnanocompositematsofcellulosenanocrystals(CNCs)incombinationwithPLAandmaleicanhydridegraftedPLA(MPLA)wereelectrospunfromasolventmixtureconsistingofN,N‘-dimethylformamideandchloroform.Morphological,mechanicalandthermalpropertieswerecharacterizedaswellasthein-vitrodegradationratesandhumanadultadiposederivedmesenchymalcellsviabilityasafunctionoffibercomposition.AveragediameteroftheelectrospunfibersdecreasedwiththeadditionofCNCinthematrix.MPLAnanocompositefibershadsmallerdiameterscomparedtoPLAcompositefibers.TensilestrengthandmodulusofthenanocompositeswereimprovedwiththeadditionofCNCsuptothe5wt%levelduetoCNCreinforcementandincreasedcomposite‘scrystallinity.ElongationofnanocompositesdecreasedsharplyatthehigherCNCcontentlevelduetotheaggregationofCNCsinmatrix.ThermalstabilityofPLAandMPLAwasimprovedfornanocompositeswithsmallerCNCcontents.Resultsofin-vitrodegradationandcellviabilityassasysindicatedthatMPLAnanocompositeshadexcellentbiodegradabilityandbiocompatibility.
作者: C. J. Zhou, Q. F. Shi, R. Z. Huang, Q. L. Wu
上傳時間: 2013-06-21 15:12:52
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